What are the main factors that influence an Advanced Clinical Specialist's salary?

The primary factors are: 1) Experience Level, 2) Geographic Location, 3) Education/Skills, 4) Company Size & Industry

How does experience change An Advanced Clinical Specialist's salary?

An Advanced Clinical Specialist's salary grows with experience: starting around $64,499 for beginners, reaching about $93,060 at mid-level, and approach $102,396 for experts.

What are the highest paying states for an Advanced Clinical Specialist?

Advanced Clinical Specialist salary varies significantly by state. The top 3 highest paying states for Advanced Clinical Specialist roles are District of Columbia $89,188, California $88,850, Massachusetts $87,666. These tech hubs typically pay 10-15% above the national average.

How much do different types of Advanced Clinical Specialist roles make?

Salaries for Advanced Clinical Specialist level roles vary by specialization: Clinical Education Specialist V: $150,903; Advanced Clinical Practitioner: $116,381; Advanced Analytics Specialist: $101,364; Advanced Clinical Education Specialist: $83,330; Advanced Compliance Specialist: $79,873.

Advanced Clinical Specialist Salary in the United States

How much does an Advanced Clinical Specialist make in the United States? As of September 01, 2026, the average salary for an Advanced Clinical Specialist in the United States is $80,553 per year, which breaks down to an hourly rate of $39.

However, an Advanced Clinical Specialist's salary can vary significantly. Here's a look at the typical salary range:

Top Earners (90th percentile): $91,419
Majority Range (25th-75th percentile): $71,922 to $86,241
Entry-Level (10th percentile): $64,063

10% $64,063

50% (Median) $80,553

90% $91,419

Advanced Clinical Specialist Salaries by Percentile

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$86,241	$7,187	$1,658	$41
Average	$80,553	$6,713	$1,549	$39
25th Percentile	$71,922	$5,993	$1,383	$35

Salary Factors Salary-Boosting Skills Salary by Experience Related Job Salaries Top Paying Cities Explore Related Jobs

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Key Factors That Influence Advanced Clinical Specialist Salaries

An Advanced Clinical Specialist's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

How Experience Level Affects Advanced Clinical Specialist Salaries?

Experience is a primary driver of an Advanced Clinical Specialist's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

Entry-Level (less than 1 year): $64,499
Early Career (1-2 years): $79,368
Mid-Level (2-4 years): $93,060
Senior-Level (5-8 years): $117,482
Expert (over 8 years): $102,396

Job Role	Years of Experience	Average Salary
System Documentation Specialist I	less than 1 year	$64,499
Advanced Clinical Specialist	1-2 years	$79,368
System Documentation Specialist III	2-4 years	$93,060
System Documentation Specialist IV	5-8 years	$117,482
System Documentation Supervisor	over 8 years	$102,396

How Do Advanced Clinical Specialist Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Advanced Clinical Specialists. For example, consider the average annual salaries in these key locations:

District of Columbia: $89,188.
California: $88,850.
Massachusetts: $87,666.

District of Columbia $89,188 California $88,850 Massachusetts $87,666 Washington $87,344 New Jersey $87,312 Alaska $87,199 Connecticut $86,087 New York $85,636

Hawaii $84,194 Rhode Island $83,517 Maryland $83,058 Minnesota $82,430 Colorado $82,188 Illinois $82,108 Oregon $81,802 Delaware $81,576

New Hampshire $81,434 Virginia $81,117 Pennsylvania $80,191 Nevada $79,723 North Dakota $79,570 Michigan $79,329 Wisconsin $79,240 Vermont $79,063

Texas $78,571 Maine $78,539 Arizona $78,491 Ohio $78,435 Georgia $77,693 Indiana $77,323 Wyoming $77,250 Utah $77,138

Iowa $77,089 Kansas $76,703 Louisiana $76,590 North Carolina $76,550 Missouri $76,534 Florida $76,219 Montana $76,050 Nebraska $75,889

Kentucky $75,800 South Carolina $75,478 Tennessee $75,277 Idaho $75,196 New Mexico $74,608 Oklahoma $74,479 Alabama $74,004 South Dakota $73,207

Arkansas $72,772 West Virginia $72,538 Mississippi $71,837

Top Paying Cities for Advanced Clinical Specialist

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

San Jose: $101,602
San Francisco: $100,489
Oakland: $98,371

San Jose, CA $101,602

San Francisco, CA $100,489

Oakland, CA $98,371

New York, NY $92,748

Paramus, NJ $91,620

Queens Village, NY $91,616

Passaic, NJ $91,540

Bergenfield, NJ $91,532

Stamford, CT $91,355

Huntington, NY $91,322

Newark, NJ $90,727

Bridgeport, CT $90,557

Vallejo, CA $90,397

New Brunswick, NJ $90,364

Petaluma, CA $90,316

Middlesex, NJ $90,163

Somerset, NJ $90,107

Santa Cruz, CA $90,002

Boston, MA $89,511

Monterey, CA $89,228

Seattle, WA $89,043

Santa Rosa, CA $89,027

Los Angeles, CA $89,003

Juneau, AK $88,794

Washington, DC $88,705

Orange, CA $88,418

Santa Ana, CA $88,206

Long Beach, CA $88,125

Anaheim, CA $88,109

Anchorage, AK $88,069

Santa Maria, CA $87,827

Everett, WA $87,811

Danbury, CT $87,527

Bremerton, WA $87,416

Tacoma, WA $87,126

New Suffolk, NY $87,125

Sacramento, CA $87,102

Santa Barbara, CA $87,013

San Diego, CA $86,925

Trenton, NJ $86,925

Brockton, MA $86,836

Fairbanks, AK $86,639

Lompoc, CA $86,433

Lowell, MA $86,368

Ventura, CA $86,353

Nashua, NH $86,337

Stockton, CA $86,329

Modesto, CA $85,741

Poughkeepsie, NY $85,564

Olympia, WA $85,410

Kennewick, WA $85,410

New Haven, CT $85,378

Lawrence, MA $85,088

Hartford, CT $85,008

Riverside, CA $84,992

New Bedford, MA $84,911

Richland, WA $84,911

Bakersfield, CA $84,798

San Bernardino, CA $84,766

New Britain, CT $84,758

Atlantic City, NJ $84,758

New London, CT $84,726

Norwich, CT $84,702

Portsmouth, NH $84,685

Boulder, CO $84,515

Portland, OR $84,404

Worcester, MA $84,395

Minneapolis, MN $84,146

Philadelphia, PA $84,033

Honolulu, HI $83,767

Saint Paul, MN $83,729

Vineland, NJ $83,711

Providence, RI $83,477

Chicago, IL $83,244

Bellingham, WA $83,147

Springfield, MA $83,082

Baltimore, MD $83,058

Chico, CA $82,857

Pittsfield, MA $82,639

Manchester, NH $82,486

Spokane, WA $82,132

Denver, CO $82,124

Albany, NY $81,745

Troy, NY $81,713

Nassau, NY $81,627

Schenectady, NY $81,544

Wilmington, DE $81,479

Burlington, VT $81,367

Salem, OR $81,334

Portland, ME $81,085

Yakima, WA $81,004

Rochester, MN $80,754

Reno, NV $80,714

Fresno, CA $80,714

Milwaukee, WI $80,642

Detroit, MI $80,561

Ann Arbor, MI $80,547

Allentown, PA $80,537

Colorado Springs, CO $80,400

Syracuse, NY $80,360

Carson City, NV $80,360

Houston, TX $80,247

Eugene, OR $80,207

Gary, IN $80,110

Springfield, OR $80,046

Bismarck, ND $80,030

Galveston, TX $79,973

Medford, OR $79,852

Fort Collins, CO $79,820

Concord, NH $79,780

Austin, TX $79,756

Mesa, AZ $79,586

Reading, PA $79,578

Phoenix, AZ $79,570

Dallas, TX $79,546

Saint Cloud, MN $79,469

Madison, WI $79,361

Utica, NY $79,143

Rochester, NY $79,015

Des Moines, IA $79,006

Raleigh, NC $78,998

Atlanta, GA $78,878

Battle Creek, MI $78,853

Salt Lake City, UT $78,829

Lancaster, PA $78,708

Harrisburg, PA $78,596

Kansas City, MO $78,515

Kansas City, KS $78,499

Champaign, IL $78,499

Fort Worth, TX $78,491

Columbus, OH $78,477

Boca Raton, FL $78,459

Pittsburgh, PA $78,426

Richmond, VA $78,394

Indianapolis, IN $78,378

Cleveland, OH $78,370

Las Vegas, NV $78,273

Cincinnati, OH $78,273

Petersburg, VA $78,153

Huntsville, AL $78,032

Lansing, MI $77,978

Lebanon, PA $77,967

Pueblo, CO $77,959

Appleton, WI $77,935

Buffalo, NY $77,903

Dayton, OH $77,879

Racine, WI $77,863

Charlotte, NC $77,855

Saint Louis, MO $77,830

York, PA $77,782

Elkhart, IN $77,782

Gastonia, NC $77,767

Billings, MT $77,747

Beaumont, TX $77,726

Lorain, OH $77,710

Benton Harbor, MI $77,693

Toledo, OH $77,677

Binghamton, NY $77,637

Rock Hill, SC $77,629

Rockford, IL $77,589

Springfield, IL $77,557

Elyria, OH $77,548

Fargo, ND $77,548

Flagstaff, AZ $77,492

Fort Lauderdale, FL $77,444

Duluth, MN $77,395

Miami, FL $77,395

Grand Forks, ND $77,339

Cheyenne, WY $77,339

Bangor, ME $77,162

Cedar Rapids, IA $77,073

Durham, NC $77,039

Louisville, KY $77,033

Grand Rapids, MI $77,017

Hialeah, FL $77,009

Casper, WY $76,896

Scranton, PA $76,799

New Orleans, LA $76,775

Virginia Beach, VA $76,767

Akron, OH $76,727

Peoria, IL $76,622

Sarasota, FL $76,606

Nashville, TN $76,550

Omaha, NE $76,550

Green Bay, WI $76,550

Baton Rouge, LA $76,509

Charleston, SC $76,493

Davenport, IA $76,453

Jamestown, NY $76,453

Tucson, AZ $76,413

Saint Petersburg, FL $76,364

Tampa, FL $76,348

Evansville, IN $76,300

Port Arthur, TX $76,300

Bradenton, FL $76,268

Santa Fe, NM $76,123

Orlando, FL $75,978

Clearwater, FL $75,954

La Crosse, WI $75,784

Canton, OH $75,784

Albuquerque, NM $75,736

Newport News, VA $75,728

High Point, NC $75,704

Ogden, UT $75,672

Corpus Christi, TX $75,607

Norfolk, VA $75,559

Laramie, WY $75,559

Rock Island, IL $75,510

Saginaw, MI $75,494

Jacksonville, FL $75,486

Salisbury, NC $75,470

Boise, ID $75,454

Moline, IL $75,414

Fort Myers, FL $75,390

Memphis, TN $75,374

Tulsa, OK $75,333

Waterloo, IA $75,285

Spartanburg, SC $75,204

Lincoln, NE $75,164

Fort Wayne, IN $75,148

Provo, UT $75,140

Cedar Falls, IA $75,043

San Antonio, TX $75,011

Greensboro, NC $74,979

South Bend, IN $74,971

Savannah, GA $74,882

Muskegon, MI $74,850

Birmingham, AL $74,842

Winston Salem, NC $74,802

Lake Charles, LA $74,608

Anderson, IN $74,592

Lexington, KY $74,568

Augusta, GA $74,544

Greenville, SC $74,544

Lima, OH $74,479

Wichita, KS $74,471

Tuscaloosa, AL $74,471

Columbia, SC $74,399

Springfield, OH $74,383

Asheville, NC $74,254

Bloomington, IN $74,197

Knoxville, TN $73,907

Shreveport, LA $73,899

Wilmington, NC $73,795

Roanoke, VA $73,795

Topeka, KS $73,650

Frankfort, KY $73,641

Oklahoma City, OK $73,585

Chillicothe, OH $73,553

Longview, TX $73,545

Melbourne, FL $73,537

Sioux Falls, SD $73,408

Mobile, AL $73,400

Terre Haute, IN $73,368

Altoona, PA $73,319

Amarillo, TX $73,263

Killeen, TX $73,239

Fayetteville, AR $73,174

Chattanooga, TN $73,150

Sioux City, IA $73,078

Idaho Falls, ID $73,062

Lynchburg, VA $72,997

Gainesville, FL $72,893

Portsmouth, OH $72,852

Little Rock, AR $72,836

Lafayette, LA $72,804

Youngstown, OH $72,804

Daytona Beach, FL $72,756

Clarksville, TN $72,748

Pensacola, FL $72,739

Temple, TX $72,734

Hopkinsville, KY $72,498

Erie, PA $72,482

Florence, SC $72,449

Charleston, WV $72,321

Great Falls, MT $72,280

Macon, GA $72,168

Tallahassee, FL $72,159

Fayetteville, NC $72,143

Waco, TX $72,127

Helena, MT $72,071

Pine Bluff, AR $72,040

Vincennes, IN $71,942

Lubbock, TX $71,910

Alamogordo, NM $71,861

Twin Falls, ID $71,789

Rapid City, SD $71,765

Jackson, MS $71,620

Huntington, WV $71,614

Greenville, MS $71,612

Parkersburg, WV $71,530

Montgomery, AL $71,515

Wichita Falls, TX $71,434

Springfield, MO $71,434

Biloxi, MS $71,394

Monroe, LA $71,314

Johnstown, PA $71,257

Sumter, SC $71,225

Columbus, GA $71,217

Pascagoula, MS $71,064

Abilene, TX $71,064

Kingsport, TN $70,855

Albany, GA $70,855

Gulfport, MS $70,830

Alexandria, LA $70,565

Fort Smith, AR $70,363

El Paso, TX $70,146

Las Cruces, NM $69,783

Harlingen, TX $69,579

Pocatello, ID $69,566

Florence, AL $69,461

Brownsville, TX $69,445

Mcallen, TX $69,276

Dothan, AL $69,163

Columbus, MS $68,684

Altus, OK $68,309

Lawton, OK $68,156

Pierre, SD $67,866

Advanced Clinical Specialist Salary by Industry: Top Paying Sectors

For Advanced Clinical Specialist roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Biotechnology and Aerospace & Defense sectors offer the strongest compensation, at 26% above the average. In contrast, Advanced Clinical Specialist positions in Hospitality & Leisure or Media typically offer lower base pay, as these industries often view Advanced Clinical Specialist as a support function rather than a direct revenue driver.

The top paying industries for an Advanced Clinical Specialist

Industry Sector	Average Annual Salary	Average Hourly Rate	Pay vs.Avg
Biotechnology	$101,497	$49.0	26%
Aerospace & Defense	$87,803	$42.0	9%
Internet	$86,192	$41.0	7%
Healthcare	$85,386	$41.0	6%
Software & Networking	$85,386	$41.0	6%

How Education impacts an Advanced Clinical Specialist's Salary?

Your level of education can impact your salary potential. While many Advanced Clinical Specialist professionals enter the field with a high school degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for an Advanced Clinical Specialist with a high school is between $68,514 and $72,616.

Advanced Clinical Specialist Salaries by Degree Level

$74,100
$73,300
$72,500
$71,700
$71,000
$70,200
$69,400
$68,600

Typical Education for Advanced Clinical Specialist
Degree Level	% of user with this level of education
No Degree	23%
High School	23%
Associate's Degree	14.1%
Bachelor's Degree	44.6%
Master's Degree or MBA	17.4%
JD, MD, PhD or Equivalent	0.9%

View as Graph

Advanced Clinical Specialist Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how an Advanced Clinical Specialist's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

$71,922

Average $80,553/year

$86,241

$5,993

Average $6,713/month

$7,187

$1,383

Average $1,549/week

$1,658

$35

Average $39/hour

$41

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$86,241	$7,187	$1,658	$41
Average	$80,553	$6,713	$1,549	$39
25th Percentile	$71,922	$5,993	$1,383	$35

Salary Trends for Advanced Clinical Specialist

Salaries for an Advanced Clinical Specialist can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $82,752 in 2023 to around $82,573 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Advanced Clinical Specialist salary trends, click here.

Average Annual Salary of Advanced Clinical Specialist Over Time

$???
$82,752
$83,280
$82,573
$???
$???

2022
2023
2024
2025
2026
2027

Year	Average Annual Salary
2022	View More
2023	$82,752
2024	$83,280
2025	$82,573

Most common benefits for Advanced Clinical Specialist

Social Security
401 (k)
Disability
Healthcare
Pension
Time Off (days)

Common company salaries for Advanced Clinical Specialist

Here are companies hiring for Advanced Clinical Specialist and their salaries, click below for more details.

C $128,509/per year

C R Bard Inc Biotechnology United States

H $124,697/per year

Henry Schein Canada Biotechnology United States

N $123,899/per year

Nordex Inc Biotechnology United States

N $120,416/per year

Nipro Corp Biotechnology United States

E $115,870/per year

Enovis Biotechnology United States

A $114,553/per year

Advanced Research Projects Agency - Energy Biotechnology United States

M $112,110/per year

MiniMed Inc Biotechnology United States

L $111,500/per year

Labcorp Drug Development Biotechnology United States

L $110,229/per year

Life Technologies Corp Biotechnology United States

Z $106,224/per year

Zimmer Biomet Biotechnology United States

P $103,077/per year

Promontory Therapeutics Biotechnology United States

S $102,181/per year

Steris PLC Biotechnology United States

G $97,274/per year

Gavin Conferences Pty Ltd Biotechnology United States

E $94,764/per year

Endeavor BioMedicines Biotechnology United States

R $94,402/per year

Replay Holdings LLC Biotechnology United States

P $94,235/per year

Pleno Inc Biotechnology United States

S $93,666/per year

Simulaids Inc Biotechnology United States

N $88,880/per year

NOIRLab/CAS Biotechnology United States

O $86,468/per year

Onward Technology Biotechnology United States

L $84,895/per year

LED Medical Diagnostics Inc Biotechnology United States

E $84,682/per year

Eyeco Ltd Biotechnology United States

P $84,523/per year

Paerosol Biotechnology United States

I $83,525/per year

IONIQ Sciences Inc Biotechnology United States

S $82,815/per year

Stateside PPE Biotechnology United States

D $82,041/per year

Digi Bio Biotechnology United States

Find Your Next Advanced Clinical Specialist Job

Ready to take the next step in your career? Browse thousands of current Advanced Clinical Specialist job openings on our job board. Use the search bar below to find your perfect match.

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Find your next job here. Will train the right candidate. Average salaries from $20 - $37/Hr, full time and part time shifts available now. Hiring for: Clin... more

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US Government Jobs | Columbus, OH

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US Government Jobs | Columbus, OH

Facility PMOP Coordinator. The Facility PMOP Coordinator is located at the main Central Ohio VA Healthcare Center, (Chalmers P. Wylie VA ACC). The Facility... more

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US Department of Veterans Affairs | Columbus, OH

Pharmacist

US Department of Veterans Affairs | Columbus, OH

Facility PMOP Coordinator. The duties for the Facility PMOP Coordinator include (but are not limited to). Supports a high functioning Pain Committee that i... more

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Nuclear Medicine Technologist -- Clinical Research Specialist - Radiology. The Nuclear Medicine Technologist -- Clinical Research Specialist is responsible... more

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FAQ about Advanced Clinical Specialist

1. What industry pays the highest salary for Advanced Clinical Specialist?

The Biotechnology industry offers the highest average compensation for Advanced Clinical Specialist roles, with salaries approximately 26% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

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Advanced Clinical Specialist Salary in the United States

Check out Advanced Clinical Specialist Job Openings in the United States

Key Factors That Influence Advanced Clinical Specialist Salaries

How Experience Level Affects Advanced Clinical Specialist Salaries?

How Do Advanced Clinical Specialist Salaries Vary from State to State?

Top Paying Cities for Advanced Clinical Specialist

Advanced Clinical Specialist Salary by Industry: Top Paying Sectors

The top paying industries for an Advanced Clinical Specialist

How Education impacts an Advanced Clinical Specialist's Salary?

Advanced Clinical Specialist Salaries by Degree Level

Typical Education for Advanced Clinical Specialist

Advanced Clinical Specialist Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Salary Trends for Advanced Clinical Specialist

Average Annual Salary of Advanced Clinical Specialist Over Time

Most common benefits for Advanced Clinical Specialist

Common company salaries for Advanced Clinical Specialist

Find Your Next Advanced Clinical Specialist Job

For Employees

For Employers

FAQ about Advanced Clinical Specialist

1. What industry pays the highest salary for Advanced Clinical Specialist?

Where Does Our Salary Data Come From?

Are you an HR manager or compensation specialist?

Advanced Clinical Specialist Salary in the United States

Check out Advanced Clinical Specialist Job Openings in the United States

Key Factors That Influence Advanced Clinical Specialist Salaries

How Experience Level Affects Advanced Clinical Specialist Salaries?

How Do Advanced Clinical Specialist Salaries Vary from State to State?

Top Paying Cities for Advanced Clinical Specialist

Advanced Clinical Specialist Salary by Industry: Top Paying Sectors

The top paying industries for an Advanced Clinical Specialist

How Education impacts an Advanced Clinical Specialist's Salary?

Advanced Clinical Specialist Salaries by Degree Level

Typical Education for Advanced Clinical Specialist

Advanced Clinical Specialist Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Salaries of jobs related to Advanced Clinical Specialist

Salary Trends for Advanced Clinical Specialist

Average Annual Salary of Advanced Clinical Specialist Over Time

Most common benefits for Advanced Clinical Specialist

Common company salaries for Advanced Clinical Specialist

Find Your Next Advanced Clinical Specialist Job

For Employees

For Employers

FAQ about Advanced Clinical Specialist

1. What industry pays the highest salary for Advanced Clinical Specialist?

Where Does Our Salary Data Come From?

Are you an HR manager or compensation specialist?