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How much does an Associate Director of Clinical Research Operations make in the United States? As of September 01, 2026, the average salary for an Associate Director of Clinical Research Operations in the United States is $165,409 per year, which breaks down to an hourly rate of $80.
However, an Associate Director of Clinical Research Operations's salary can vary significantly. Here's a look at the typical salary range:
Associate Director of Clinical Research Operations Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
|---|---|---|---|---|
| 75th Percentile | $177,409 | $14,784 | $3,412 | $85 |
| Average | $165,409 | $13,784 | $3,181 | $80 |
| 25th Percentile | $151,228 | $12,602 | $2,908 | $73 |
An Associate Director of Clinical Research Operations's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.
Experience is a primary driver of an Associate Director of Clinical Research Operations's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Job Role | Years of Experience | Average Salary |
|---|---|---|
| Clinical Research Associate II | less than 1 year | $71,326 |
| Scientist - Clinical Research | 1-2 years | $101,306 |
| Clinical Research Manager | 2-4 years | $109,428 |
| Associate Director of Clinical Research Operations | 5-8 years | $162,909 |
| VP of Clinical Research | over 8 years | $251,273 |
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Associate Director of Clinical Research Operations. For example, consider the average annual salaries in these key locations:
Your level of education can impact your salary potential. While many Associate Director of Clinical Research Operations professionals enter the field with a Master's degree, higher education can lead to more specialized and higher-paying roles.
According to our 100% employer-reported salary data, the median salary for an Associate Director of Clinical Research Operations with a Master's is between $154,661 and $165,322.
| Typical Education for Associate Director of Clinical Research Operations | |
|---|---|
| Degree Level | % of user with this level of education |
| No Degree | 4% |
| High School | 4% |
| Associate's Degree | 2% |
| Bachelor's Degree | 32% |
| Master's Degree or MBA | 40% |
| JD, MD, PhD or Equivalent | 22% |
Understanding how an Associate Director of Clinical Research Operations's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $177,409 | $14,784 | $3,412 | $85 |
| Average | $165,409 | $13,784 | $3,181 | $80 |
| 25th Percentile | $151,228 | $12,602 | $2,908 | $73 |
Salaries for an Associate Director of Clinical Research Operations can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $166,365 in 2023 to around $157,329 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Associate Director of Clinical Research Operations salary trends, click here.
| Year | Average Annual Salary |
|---|---|
| 2022 | View More |
| 2023 | $166,365 |
| 2024 | $161,105 |
| 2025 | $157,329 |
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The Healthcare industry offers the highest average compensation for Associate Director of Clinical Research Operations roles, with salaries approximately 10% above the market median.
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