Safety Manager
Hearthside Food Solutions – North Sioux City, SD
Know your market value with insights across roles — from individual contributors to executive pay and overall company compensation trends.
Access a suite of powerful calculators to make data-driven career decisions.
Automate pay cycles, manage job architectures, and ensure pay equity with AI-powered compensation platforms.
Access validated salary benchmarks, labor market trends, and minimum wage data to stay competitive.
Participate in and purchase industry-specific salary surveys to obtain the most accurate, peer-reported pay data.
How much does a Drug Safety Manager make in South Dakota? As of September 01, 2026, the average salary for a Drug Safety Manager in South Dakota is $90,959 per year, which breaks down to an hourly rate of $44.
However, a Drug Safety Manager's salary can vary significantly. Here's a look at the typical salary range:
Drug Safety Manager Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
|---|---|---|---|---|
| 75th Percentile | $102,121 | $8,510 | $1,964 | $49 |
| Average | $90,959 | $7,580 | $1,749 | $44 |
| 25th Percentile | $81,001 | $6,750 | $1,558 | $39 |
A Drug Safety Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Drug Safety Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Job Role | Years of Experience | Average Salary |
|---|---|---|
| Entry Level Drug Safety Manager | less than 1 year | $84,739 |
| Early Career Level Drug Safety Manager | 1-2 years | $85,207 |
| Mid-Level Level Drug Safety Manager | 2-4 years | $86,765 |
| Senior-Level Level Drug Safety Manager | 5-8 years | $88,634 |
| Expert Level Drug Safety Manager | over 8 years | $91,269 |
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Drug Safety Managers. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Drug Safety Manager roles, the industry you choose can affect earning potential by as much as 30% (the gap between the highest and lowest paying industries). Data shows that the Edu., Gov't. & Nonprofit and Insurance sectors offer the strongest compensation, at 10% above the average. In contrast, Drug Safety Manager positions in Business Services or Financial Services typically offer lower base pay, as these industries often view Drug Safety Manager as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Edu., Gov't. & Nonprofit | $100,055 | $48.0 | 10% |
| Insurance | $100,055 | $48.0 | 10% |
Understanding how a Drug Safety Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $102,121 | $8,510 | $1,964 | $49 |
| Average | $90,959 | $7,580 | $1,749 | $44 |
| 25th Percentile | $81,001 | $6,750 | $1,558 | $39 |
Ready to take the next step in your career? Browse thousands of current Drug Safety Manager job openings on our job board. Use the search bar below to find your perfect match.
Takkion | Sioux Falls, SD
Takkion | Sioux Falls, SD
Job TypeFull-timeDescriptionWe are looking for an outgoing and driven candidate to join our team as a Safety & Technical Trainer. You will get to train new... more
7 Days Ago
US Veterans Health Administration | Sioux Falls, SD
US Veterans Health Administration | Sioux Falls, SD
Summary Join the Sioux Falls VA Health Care System as a Patient Safety Informatics Registered Nurse and help drive safer, smarter care for Veterans.This hi... more
10 Days Ago
Maguire Iron Inc | Sioux Falls, SD
Maguire Iron Inc | Sioux Falls, SD
For over 100 years, Maguire has been an industry leader in the fabrication, construction, and maintenance of water storage tanks and elevated water towers.... more
7 Days Ago
Dean Kurtz Construction | Fort Thompson, SD
Dean Kurtz Construction | Fort Thompson, SD
Dean Kurtz Construction is hiring an SSHO for a USACE project at Ft Thompson, SD The Site Safety & Health Officer (SSHO) will have primary responsibility f... more
7 Days Ago
ProSidian | Sioux Falls, SD
ProSidian | Sioux Falls, SD
[Administrative Assistant / Fully Remote] - Anywhere in U.S. / Competitive pay / Medical, dental and vision / 401k / PTO - As a Data Entry Assistant you'll... more
11 Days Ago
ProSidian | Watertown, SD
ProSidian | Watertown, SD
[Administrative Assistant / Fully Remote] - Anywhere in U.S. / Competitive pay / Medical, dental and vision / 401k / PTO - As a Data Entry Assistant you'll... more
11 Days Ago
Analyze the market and your qualifications to negotiate your salary with confidence.
Search thousands of open positions to find your next opportunity.
Individualize employee pay based on unique job requirements and personal qualifications.
Get the latest market price for benchmark jobs and jobs in your industry.
Salary.com salary estimates, histograms, trends, and comparisons are derived from both employer job postings and third-party data sources. We also provide multiple percentiles of salary information for your reference, click here to know Why the Salary Midpoint Formula Is Crucial to Getting Pay Equity Right. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.
Salary.com's CompAnalyst platform offers: