What is the average Physician Assistant salary for Sioux Falls, SD?
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As of June 01, 2026, the average Physician Assistant salary in Sioux Falls, SD is $102,857. The chart below represents localized salaries for some of our most popular Physician Assistant job titles in Sioux Falls, SD. Salaries can vary greatly depending on numerous factors, including position, location, years of experience, and level of education. Salary.com’s team of Certified Compensation Professionals analyzed survey data collected from thousands of HR departments at companies of all sizes and industries to compile a range of salaries for various Physician Assistant job titles in Sioux Falls, SD. Apply your personal criteria to one of the job titles below to get your personalized salary estimate.
Physician Assistant Salaries in Sioux Falls, SD
| Job Title | Salary | Hourly Rate | Location | Date Updated |
| Physician Assistant - Cardiology | $122,652 | $58.97 | Sioux Falls, SD | June 01, 2026 |
| Physician Assistant - Clinic | $128,546 | $61.80 | Sioux Falls, SD | June 01, 2026 |
| Physician Assistant - Orthopedics | $125,060 | $60.13 | Sioux Falls, SD | June 01, 2026 |
| Physician Assistant - Primary Care | $118,602 | $57.02 | Sioux Falls, SD | June 01, 2026 |
| Physician Assistant - Surgical | $126,590 | $60.86 | Sioux Falls, SD | June 01, 2026 |
| Physician Assistant - Medical | $119,797 | $57.59 | Sioux Falls, SD | June 01, 2026 |
| Physician Assistant - Specialty | $134,157 | $64.50 | Sioux Falls, SD | June 01, 2026 |
| Physician Assistant - Emergency & Trauma | $136,588 | $65.67 | Sioux Falls, SD | June 01, 2026 |
| Physician Recruiter | $85,343 | $41.03 | Sioux Falls, SD | June 01, 2026 |
| Systems Support Assistant | $59,427 | $28.57 | Sioux Falls, SD | June 01, 2026 |
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Provides cardiac care to patients under the supervision of a physician. Conducts medical histories and physical exams, diagnoses and treats illnesses and injuries, and develops treatment plans. Orders and interprets diagnostic tests and laboratory work. Writes progress notes, conducts patient education, writes prescriptions, and provides advice about various health issues. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Cardiology Salaries in Sioux Falls, SDCategory : Healthcare - Practitioners
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Provides care to patients in a clinic under the supervision of a physician. Conducts medical histories and physical exams, diagnoses and treats illnesses and injuries, and develops treatment plans. Orders and interprets diagnostic tests and laboratory work. Writes progress notes, conducts patient education, writes prescriptions, and provides advice about various health issues. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Clinic Salaries in Sioux Falls, SDCategory : Healthcare - Practitioners
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Provides orthopedic care to patients under the supervision of a physician. Conducts medical histories and physical exams, diagnoses and treats illnesses and injuries, and develops treatment plans. Orders and interprets diagnostic tests and laboratory work. Writes progress notes, conducts patient education, writes prescriptions, and provides advice about various health issues. May assist in surgery. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Orthopedics Salaries in Sioux Falls, SDAlternate Job Titles:PA -Physician Assistant -Orthopedic, Physician Assistant - OrthopedicsCategory : Healthcare - Practitioners
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Provides care to patients in a primary care setting under the supervision of a physician. Conducts medical histories and physical exams, diagnoses and treats illnesses and injuries, and develops treatment plans. Orders and interprets diagnostic tests and laboratory work. Writes progress notes, conducts patient education, writes prescriptions, and provides advice about various health issues. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Primary Care Salaries in Sioux Falls, SDAlternate Job Titles:PA -Physician Assistant - Generalist, Physician Assistant - Primary CareCategory : Healthcare - Practitioners
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Provides care to patients in a surgical unit under the supervision of a physician. Responsible for providing preoperative, intraoperative, and postoperative assistance and/or care. Orders and interprets diagnostic tests and laboratory work. Writes progress notes, conducts patient education, writes prescriptions, and provides advice about various health issues. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Surgical Salaries in Sioux Falls, SDAlternate Job Titles:Certified Physician Assistant (PA) -Surgical, Physician Associate - Surgical, Physician Assistant - SurgicalCategory : Healthcare - Technicians
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Provides care to patients under the supervision of a physician. Conducts medical histories and physical exams, diagnoses and treats illnesses and injuries, and develops treatment plans. Orders and interprets diagnostic tests and laboratory work. Writes progress notes, conducts patient education, writes prescriptions, and provides advice about various health issues. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Medical Salaries in Sioux Falls, SDAlternate Job Titles:Certified Physician Assistant (PA), Physician Assistant (PA), Physician Associate - Medical, Physician Assistant - MedicalCategory : Healthcare - Practitioners
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Provides care to patients in a medical specialty (such as neurology, oncology, dermatology, etc.) under the supervision of a physician. Conducts medical histories and physical exams, diagnoses and treats illnesses and injuries, and develops treatment plans. Orders and interprets diagnostic tests and laboratory work. Writes progress notes, conducts patient education, writes prescriptions, and provides advice about various health issues. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Specialty Salaries in Sioux Falls, SDAlternate Job Titles:Certified Physician Assistant (PA)-Medical Specialty, Physician Associate - Specialty, Physician Assistant - SpecialtyCategory : Healthcare - Practitioners
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Provides care to patients in an emergency and trauma unit under the supervision of a physician. Conducts medical histories and physical exams, diagnoses and treats illnesses and injuries, and develops treatment plans. Orders and interprets diagnostic tests and laboratory work. Participates in daily patient rounds, writes progress notes, conducts patient education, writes prescriptions, and prepares discharge summaries. Requires a master's degree in health sciences for physician assistants. Requires Certified Physician Assistant (PA-C). Requires State License to practice. Typically reports to a physician. Years of experience may be unspecified. Certification and/or licensing in the position's specialty is the main requirement. Physician Assistant - Emergency & Trauma Salaries in Sioux Falls, SDAlternate Job Titles:Certified Physician Assistant (PA)-Emergency & Trauma, Physician Associate - Emergency & Trauma, Physician Assistant - Emergency & TraumaCategory : Healthcare - Practitioners
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Recruits qualified physicians for medical staff and assists and coordinates the development of strategic and comprehensive physician recruitment plans in accordance with the needs and goals of the employer and staff. Performs initial interviews to determine candidate suitability for placement. Requires a bachelor's degree in area of specialty. Typically reports to a manager or head of a unit/department. Typically requires 2 to 4 years of related experience. Gains exposure to some of the complex tasks within the job function. Occasionally directed in several aspects of the work. Physician Recruiter Salaries in Sioux Falls, SDAlternate Job Titles:Physician Talent Acquisition Specialist, Physician Recruiter
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Assists in the installation, maintenance, and general support of systems. Assists users with questions or problems. May help perform system backups and recovery and install new software. May require an associate degree or equivalent. Typically reports to a supervisor or manager. Works under moderate supervision. Gaining or has attained full proficiency in a specific area of discipline. Typically requires 1-3 years of related experience. Systems Support Assistant Salaries in Sioux Falls, SDAlternate Job Titles:General Systems Support Assistant, Systems Support Assistant