What are the main factors that influence an Advanced Practice RN's salary?

The primary factors are: 1) Experience Level, 2) Geographic Location, 3) Education/Skills, 4) Company Size & Industry

What industry pays the highest salary for Advanced Practice RN?

The Edu., Gov't. & Nonprofit industry offers the highest average compensation for Advanced Practice RN roles, with salaries approximately 20% above the market median.

How does experience change An Advanced Practice RN's salary?

An Advanced Practice RN's salary grows with experience: starting around $109,334 for beginners, reaching about $111,968 at mid-level, and approach $115,442 for experts.

What are the highest paying states for an Advanced Practice RN?

Advanced Practice RN salary varies significantly by state. The top 3 highest paying states for Advanced Practice RN roles are District of Columbia $133,924, California $133,416, Massachusetts $131,638. These tech hubs typically pay 10-15% above the national average.

How much do different types of Advanced Practice RN roles make?

Salaries for Advanced Practice RN level roles vary by specialization: Advanced Practice Clinician: $122,810; Advanced practice nurse educator: $121,904; Advanced Practice Nurse Prescriber: $120,282; Advanced Practice Nurse Practitioner: $115,552; Advanced Practice Nurse: $115,423.

Advanced Practice RN Salary in South Carolina

How much does an Advanced Practice RN make in South Carolina? As of September 01, 2026, the average salary for an Advanced Practice RN in South Carolina is $113,337 per year, which breaks down to an hourly rate of $54.

However, an Advanced Practice RN's salary can vary significantly. Here's a look at the typical salary range:

Top Earners (90th percentile): $127,817
Majority Range (25th-75th percentile): $107,360 to $120,916
Entry-Level (10th percentile): $101,918

10% $101,918

50% (Median) $113,337

90% $127,817

Advanced Practice RN Salaries by Percentile

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$120,916	$10,076	$2,325	$58
Average	$113,337	$9,445	$2,180	$54
25th Percentile	$107,360	$8,947	$2,065	$52

Salary Factors Salary by Experience Related Job Salaries Top Paying Cities Explore Related Jobs

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Check out Advanced Practice RN Job Openings in South Carolina

Advanced Practice Provider

Carolina Psychiatry – Greenville, SC

Advanced Practice Provider

ReGenesis Health Care – Gaffney, SC

Advanced Practice Provider

Beaufort Memorial Hospital – Hilton Head Island, SC

Advanced Practice Provider

Cardiovascular Associates of America – Lancaster, SC

Key Factors That Influence Advanced Practice RN Salaries

An Advanced Practice RN's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Advanced Practice RN Salaries?

Experience is a primary driver of an Advanced Practice RN's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

Entry-Level (less than 1 year): $109,334
Early Career (1-2 years): $109,783
Mid-Level (2-4 years): $111,968
Senior-Level (5-8 years): $114,916
Expert (over 8 years): $115,442

Job Role	Years of Experience	Average Salary
Entry Level Advanced Practice RN	less than 1 year	$109,334
Early Career Level Advanced Practice RN	1-2 years	$109,783
Mid-Level Level Advanced Practice RN	2-4 years	$111,968
Senior-Level Level Advanced Practice RN	5-8 years	$114,916
Expert Level Advanced Practice RN	over 8 years	$115,442

How Do Advanced Practice RN Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Advanced Practice RNs. For example, consider the average annual salaries in these key locations:

District of Columbia: $133,924.
California: $133,416.
Massachusetts: $131,638.

District of Columbia $133,924 California $133,416 Massachusetts $131,638 Washington $131,154 New Jersey $131,105 Alaska $130,936 Connecticut $129,267 New York $128,589

Hawaii $126,424 Rhode Island $125,408 Maryland $124,719 Minnesota $123,775 Colorado $123,412 Illinois $123,291 Oregon $122,832 Delaware $122,493

New Hampshire $122,280 Virginia $121,804 Pennsylvania $120,413 Nevada $119,711 North Dakota $119,481 Michigan $119,118 Wisconsin $118,985 Vermont $118,719

Texas $117,981 Maine $117,933 Arizona $117,861 Ohio $117,776 Georgia $116,663 Indiana $116,107 Wyoming $115,998 Utah $115,828

Iowa $115,756 Kansas $115,175 Louisiana $115,006 North Carolina $114,945 Missouri $114,921 Florida $114,450 Montana $114,196 Nebraska $113,954

Kentucky $113,821 South Carolina $113,337 Tennessee $113,034 Idaho $112,913 New Mexico $112,030 Oklahoma $111,837 Alabama $111,123 South Dakota $109,926

Arkansas $109,273 West Virginia $108,922 Mississippi $107,869

Top Paying Cities for Advanced Practice RN

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

Spartanburg: $112,925
Boiling Springs: $112,930
Arcadia: $112,925

Spartanburg, SC $112,925

Boiling Springs, SC $112,930

Arcadia, SC $112,925

Buffalo, SC $112,397

Campobello, SC $112,159

Chesnee, SC $112,619

Clifton, SC $112,911

Clinton, SC $111,132

Converse, SC $112,939

Cowpens, SC $112,777

Cross Anchor, SC $112,142

Cross Hill, SC $110,159

Drayton, SC $112,928

Duncan, SC $112,650

Enoree, SC $112,182

Fairforest, SC $112,925

Fingerville, SC $112,507

Gaffney, SC $113,077

Glendale, SC $112,954

Alcolu, SC $107,013

Ballentine, SC $111,617

Bamberg, SC $109,166

Batesburg, SC $110,580

Bethune, SC $109,442

Bishopville, SC $108,255

Blackstock, SC $112,375

Blair, SC $111,599

Blythewood, SC $111,445

Bowman, SC $109,158

Camden, SC $110,101

Cameron, SC $108,941

Carlisle, SC $111,967

Cassatt, SC $109,395

Cayce, SC $111,716

Chapin, SC $111,225

Chappells, SC $109,738

Cope, SC $109,506

Cordova, SC $109,795

Dalzell, SC $107,965

Davis Station, SC $107,938

Denmark, SC $109,424

Eastover, SC $110,314

Elgin, SC $111,162

Elliott, SC $107,868

Elloree, SC $108,997

Eutawville, SC $109,618

Gable, SC $107,017

Gadsden, SC $110,321

Gaston, SC $111,459

Gilbert, SC $111,081

Great Falls, SC $113,129

Greeleyville, SC $108,231

Heath Springs, SC $112,356

Holly Hill, SC $109,452

Hopkins, SC $111,381

Horatio, SC $109,384

Irmo, SC $111,468

Jenkinsville, SC $111,411

Kershaw, SC $110,318

Lamar, SC $108,335

Leesville, SC $110,880

Lexington, SC $111,567

Liberty Hill, SC $111,584

Little Mountain, SC $111,152

Lugoff, SC $110,654

Lydia, SC $108,465

Lynchburg, SC $107,562

Ehrhardt, SC $108,484

Lodge, SC $108,508

Mc Bee, SC $109,553

Manning, SC $107,577

Mayesville, SC $107,076

Monetta, SC $110,463

Neeses, SC $110,297

Newberry, SC $110,423

New Zion, SC $107,395

North, SC $110,538

Norway, SC $109,684

Olanta, SC $108,094

Orangeburg, SC $109,511

Peak, SC $111,337

Pelion, SC $111,013

Pinewood, SC $107,895

New Ellenton, SC $111,400

Allendale, SC $109,335

Barnwell, SC $109,891

Hilda, SC $109,541

Bath, SC $111,934

Blackville, SC $109,562

Bradley, SC $109,947

Clarks Hill, SC $111,540

Clearwater, SC $111,934

Edgefield, SC $111,026

Elko, SC $110,117

Fairfax, SC $108,977

Gloverville, SC $111,853

Graniteville, SC $111,797

Jackson, SC $111,769

Johnston, SC $110,798

Langley, SC $111,905

Mc Cormick, SC $110,209

Martin, SC $109,548

Modoc, SC $111,127

Montmorenci, SC $111,182

Mount Carmel, SC $109,447

North Augusta, SC $111,934

Beech Island, SC $111,934

Olar, SC $109,091

Parksville, SC $110,928

Plum Branch, SC $110,811

Sycamore, SC $109,054

Trenton, SC $111,335

Troy, SC $110,504

Ulmer, SC $109,032

Vaucluse, SC $111,717

Warrenville, SC $111,831

Williston, SC $110,413

Windsor, SC $110,752

Beaufort, SC $110,905

Ladys Island, SC $110,521

Okatie, SC $111,485

Bluffton, SC $111,963

Brunson, SC $108,661

Coosawhatchie, SC $110,635

Crocketville, SC $108,964

Dale, SC $110,251

Daufuskie Island, SC $112,058

Early Branch, SC $109,625

Estill, SC $109,559

Saint Helena Island, SC $110,747

Furman, SC $109,854

Garnett, SC $110,370

Gifford, SC $109,170

Hampton, SC $109,125

Hilton Head Island, SC $111,539

Hardeeville, SC $112,217

Islandton, SC $108,705

Lobeco, SC $110,321

Luray, SC $108,758

Miley, SC $108,581

Pineland, SC $110,446

Port Royal, SC $111,028

Ridgeland, SC $111,089

Scotia, SC $109,871

Seabrook, SC $110,210

Sheldon, SC $110,748

Tillman, SC $110,972

Varnville, SC $109,381

Yemassee, SC $109,743

Clemson, SC $111,091

Cleveland, SC $111,280

Conestee, SC $111,937

Donalds, SC $111,001

Inman, SC $112,659

Joanna, SC $110,764

Jonesville, SC $112,704

Kinards, SC $109,995

Landrum, SC $111,472

Laurens, SC $111,124

Lockhart, SC $112,737

Lyman, SC $112,288

Mayo, SC $112,751

Moore, SC $112,913

Mountville, SC $110,320

Pacolet, SC $112,772

Pacolet Mills, SC $112,797

Pauline, SC $112,697

Reidville, SC $112,587

Roebuck, SC $112,872

Startex, SC $112,860

Una, SC $112,925

Union, SC $112,295

Waterloo, SC $110,564

Wellford, SC $112,830

White Stone, SC $112,945

Woodruff, SC $112,461

Charleston, SC $114,861

Charleston Afb, SC $114,861

North Charleston, SC $114,861

Hanahan, SC $114,861

Adams Run, SC $113,098

Awendaw, SC $113,837

Bethera, SC $112,609

Bonneau, SC $111,450

Branchville, SC $109,000

Canadys, SC $110,185

Cordesville, SC $113,236

Cottageville, SC $112,310

Cross, SC $110,156

Dorchester, SC $111,191

Edisto Island, SC $112,765

Due West, SC $110,546

Easley, SC $111,769

Fair Play, SC $110,263

Fountain Inn, SC $111,659

Gray Court, SC $111,470

Greenwood, SC $110,181

Greer, SC $111,889

Hodges, SC $110,508

Honea Path, SC $111,228

Iva, SC $110,180

La France, SC $111,189

Liberty, SC $111,475

Long Creek, SC $109,599

Lowndesville, SC $110,221

Marietta, SC $111,468

Mauldin, SC $111,892

Mountain Rest, SC $109,865

Newry, SC $110,896

Ninety Six, SC $110,038

Norris, SC $111,306

Pelzer, SC $111,631

Pendleton, SC $111,243

Pickens, SC $111,360

Seneca, SC $110,870

Piedmont, SC $111,808

Richland, SC $110,537

Salem, SC $110,647

Sandy Springs, SC $111,095

Simpsonville, SC $111,718

Six Mile, SC $111,080

Slater, SC $111,623

Starr, SC $110,665

Sunset, SC $110,989

Tamassee, SC $110,151

Taylors, SC $111,798

Tigerville, SC $111,599

Townville, SC $110,728

Travelers Rest, SC $111,602

Walhalla, SC $110,388

Ware Shoals, SC $111,169

Westminster, SC $110,071

West Union, SC $110,679

Williamston, SC $111,496

Blacksburg, SC $114,119

Bowling Green, SC $115,726

Catawba, SC $115,832

Chester, SC $114,203

Fort Mill, SC $115,780

Chesterfield, SC $109,656

Clover, SC $115,787

Edgemoor, SC $115,801

Fort Lawn, SC $114,756

Hickory Grove, SC $113,358

Jefferson, SC $110,056

Lancaster, SC $114,220

Lando, SC $115,619

Mc Connells, SC $115,238

Mount Croghan, SC $110,212

Pageland, SC $112,150

Richburg, SC $114,671

Rock Hill, SC $116,566

Ruby, SC $109,968

Sharon, SC $113,778

Smyrna, SC $113,929

Van Wyck, SC $115,691

York, SC $115,512

Aiken, SC $111,306

Folly Beach, SC $114,861

Walterboro, SC $110,301

Williams, SC $109,075

Florence, SC $108,789

Andrews, SC $108,991

Aynor, SC $108,691

Bennettsville, SC $108,423

Blenheim, SC $108,560

Cades, SC $107,838

Centenary, SC $108,330

Cheraw, SC $109,570

Clio, SC $108,394

Conway, SC $108,686

Coward, SC $108,564

Darlington, SC $108,765

Dillon, SC $108,408

Effingham, SC $108,737

Fork, SC $108,377

Galivants Ferry, SC $108,669

Green Sea, SC $108,524

Gresham, SC $108,437

Hamer, SC $108,573

Hartsville, SC $108,818

Hemingway, SC $108,596

Johnsonville, SC $108,190

Kingstree, SC $108,675

Lake City, SC $108,094

Lake View, SC $108,584

Lane, SC $108,895

Latta, SC $108,554

Little River, SC $109,270

Little Rock, SC $108,498

Longs, SC $108,947

Loris, SC $108,641

Mc Coll, SC $108,867

Marion, SC $108,474

Myrtle Beach, SC $108,970

Minturn, SC $108,415

Mullins, SC $108,411

Murrells Inlet, SC $108,708

Nesmith, SC $108,541

Nichols, SC $108,491

North Myrtle Beach, SC $109,245

Pamplico, SC $108,454

Patrick, SC $109,506

Pawleys Island, SC $108,524

Rains, SC $108,442

Salters, SC $108,907

Scranton, SC $108,375

Sellers, SC $108,524

Society Hill, SC $108,480

Tatum, SC $108,833

Wallace, SC $109,193

Greenville, SC $111,934

Abbeville, SC $110,104

Anderson, SC $111,157

Belton, SC $111,314

Calhoun Falls, SC $109,678

Central, SC $111,193

Georgetown, SC $108,890

Goose Creek, SC $114,570

Green Pond, SC $111,475

Grover, SC $110,112

Harleyville, SC $109,859

Hollywood, SC $113,675

Huger, SC $113,487

Isle Of Palms, SC $114,839

Jacksonboro, SC $112,236

Jamestown, SC $111,860

Johns Island, SC $114,861

Ladson, SC $114,290

Mc Clellanville, SC $111,943

Moncks Corner, SC $112,668

Mount Pleasant, SC $114,861

Pineville, SC $109,235

Pinopolis, SC $111,401

Ravenel, SC $114,389

Reevesville, SC $109,305

Ridgeville, SC $112,778

Round O, SC $111,847

Ruffin, SC $109,253

Russellville, SC $109,637

Saint George, SC $109,949

Saint Stephen, SC $109,656

Smoaks, SC $108,999

Sullivans Island, SC $114,861

Summerville, SC $113,414

Wadmalaw Island, SC $114,203

Pomaria, SC $111,295

Gramling, SC $112,213

Prosperity, SC $110,941

Rembert, SC $108,905

Ridge Spring, SC $110,711

Ridgeway, SC $111,303

Rion, SC $111,473

Rowesville, SC $109,291

Saint Matthews, SC $109,962

Salley, SC $110,406

Saluda, SC $110,042

Santee, SC $109,421

Sardinia, SC $107,442

Silverstreet, SC $109,870

Springfield, SC $110,119

State Park, SC $111,713

Summerton, SC $108,465

Sumter, SC $106,950

Shaw A F B, SC $107,715

Swansea, SC $111,109

Timmonsville, SC $108,636

Turbeville, SC $107,487

Vance, SC $109,489

Wagener, SC $110,431

Ward, SC $110,456

Wedgefield, SC $108,221

West Columbia, SC $111,716

Westville, SC $110,308

White Rock, SC $111,349

Whitmire, SC $110,491

Winnsboro, SC $111,749

Columbia, SC $111,716

Advanced Practice RN Salary by Industry: Top Paying Sectors

For Advanced Practice RN roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Edu., Gov't. & Nonprofit, offers compensation 20% above the average. Conversely, Advanced Practice RN positions in Healthcare typically offer lower base pay, as this sector often view Advanced Practice RN as a support function rather than a direct revenue driver.

The top paying industry for an Advanced Practice RN

Industry Sector	Average Annual Salary	Average Hourly Rate	Pay vs.Avg
Edu., Gov't. & Nonprofit	$136,004	$65.0	20%

Advanced Practice RN Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how an Advanced Practice RN's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

$107,360

Average $113,337/year

$120,916

$8,947

Average $9,445/month

$10,076

$2,065

Average $2,180/week

$2,325

$52

Average $54/hour

$58

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$120,916	$10,076	$2,325	$58
Average	$113,337	$9,445	$2,180	$54
25th Percentile	$107,360	$8,947	$2,065	$52

Find Your Next Advanced Practice RN Job

Ready to take the next step in your career? Browse thousands of current Advanced Practice RN job openings on our job board. Use the search bar below to find your perfect match.

CVS Health | Murrells Inlet, SC

Advanced Practice Provider

CVS Health | Murrells Inlet, SC

Join CVS Health MinuteClinic. We're building a world of health around every individual shaping a more connected, convenient and compassionate health experi... more

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CVS Health | Conway, SC

Advanced Practice Provider

CVS Health | Conway, SC

Join CVS Health MinuteClinic. We're building a world of health around every individual shaping a more connected, convenient and compassionate health experi... more

10 Days Ago
MUSC | Murrells Inlet, SC

Urology Advanced Practice Provider

MUSC | Murrells Inlet, SC

Job Description. Job Description. Job Description Summary. The Medical University of South Carolina (MUSC) and Tidelands Health are seeking a Urology Advan... more

6 Days Ago
Titan Placement Group | Hartsville, SC

Psychiatric Advanced Practice Provider

Titan Placement Group | Hartsville, SC

Psychiatric Advanced Practice Provider (NP or PA). We're hiring a Psychiatric Advanced Practice Provider (NP or PA) who wants a predictable weekday schedul... more

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Cardiovascular Associates of America | Rock Hill, SC

Advanced Practice Provider Cardiology

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Advanced Practice Provider (NP/PA) Cardiology. Rock Hill, SC | Outpatient Cardiology | MondayFriday | No Call. Carolina Cardiology Associates is seeking a ... more

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Advanced Practice Provider

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Commonwealth Pain & Spine is a pain management network dedicated to improving the lives of our patients by treating their pain with the utmost respect and ... more

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Advanced Practice RN Salary in South Carolina

Check out Advanced Practice RN Job Openings in South Carolina

Key Factors That Influence Advanced Practice RN Salaries

How Experience Level Affects Advanced Practice RN Salaries?

How Do Advanced Practice RN Salaries Vary from State to State?

Top Paying Cities for Advanced Practice RN

Advanced Practice RN Salary by Industry: Top Paying Sectors

The top paying industry for an Advanced Practice RN

Advanced Practice RN Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Find Your Next Advanced Practice RN Job

For Employees

For Employers

Where Does Our Salary Data Come From?

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Advanced Practice RN Salary in South Carolina

Check out Advanced Practice RN Job Openings in South Carolina

Key Factors That Influence Advanced Practice RN Salaries

How Experience Level Affects Advanced Practice RN Salaries?

How Do Advanced Practice RN Salaries Vary from State to State?

Top Paying Cities for Advanced Practice RN

Advanced Practice RN Salary by Industry: Top Paying Sectors

The top paying industry for an Advanced Practice RN

Advanced Practice RN Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Salaries of jobs related to Advanced Practice RN

Find Your Next Advanced Practice RN Job

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