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Clinical Informatics Nurse Salary in Missouri

How much does a Clinical Informatics Nurse make in Missouri? As of September 01, 2026, the average salary for a Clinical Informatics Nurse in Missouri is $123,953 per year, which breaks down to an hourly rate of $60.

However, a Clinical Informatics Nurse's salary can vary significantly. Here's a look at the typical salary range:

  • Top Earners (90th percentile): $143,240
  • Majority Range (25th-75th percentile): $113,878 to $134,049
  • Entry-Level (10th percentile): $104,705
Salary Factors Salary by Experience Related Job Salaries Top Paying Cities Explore Related Jobs

Check out Clinical Informatics Nurse Job Openings in Missouri

Key Factors That Influence Clinical Informatics Nurse Salaries

A Clinical Informatics Nurse's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Clinical Informatics Nurse Salaries?

Experience is a primary driver of a Clinical Informatics Nurse's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $118,271
  • Early Career (1-2 years): $118,596
  • Mid-Level (2-4 years): $119,897
  • Senior-Level (5-8 years): $121,850
  • Expert (over 8 years): $124,934
Job RoleYears of ExperienceAverage Salary
Entry Level Clinical Informatics Nurse less than 1 year $118,271
Early Career Level Clinical Informatics Nurse 1-2 years $118,596
Mid-Level Level Clinical Informatics Nurse 2-4 years $119,897
Senior-Level Level Clinical Informatics Nurse 5-8 years $121,850
Expert Level Clinical Informatics Nurse over 8 years $124,934

How Do Clinical Informatics Nurse Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Informatics Nurses. For example, consider the average annual salaries in these key locations:

  • District of Columbia: $144,449.
  • California: $143,901.
  • Massachusetts: $141,983.

Top Paying Cities for Clinical Informatics Nurse

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Braggadocio: $120,109
  • Eugene: $120,599
  • Fortuna: $120,566

Clinical Informatics Nurse Salary by Industry: Top Paying Sectors

For Clinical Informatics Nurse roles, the industry you choose can impact your earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Edu., Gov't. & Nonprofit, offers compensation 20% above the average. Conversely, Clinical Informatics Nurse positions in Healthcare typically offer lower base pay, as this sector often view Clinical Informatics Nurse as a support function rather than a direct revenue driver.

The top paying industry for a Clinical Informatics Nurse

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Edu., Gov't. & Nonprofit $148,743 $72.0 20%

Clinical Informatics Nurse Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Informatics Nurse's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Yearly
  • Monthly
  • Weekly
  • Hourly
  • Table View
Last Updated on September 01, 2026
$113,878
Average $123,953/year
$134,049
$9,490
Average $10,329/month
$11,171
$2,190
Average $2,384/week
$2,578
$55
Average $60/hour
$64
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $134,049 $11,171 $2,578 $64
Average $123,953 $10,329 $2,384 $60
25th Percentile $113,878 $9,490 $2,190 $55

Find Your Next Clinical Informatics Nurse Job

Ready to take the next step in your career? Browse thousands of current Clinical Informatics Nurse job openings on our job board. Use the search bar below to find your perfect match.

  • BJC | Saint Louis, MO

    Clinical Nurse

    BJC | Saint Louis, MO

    Additional Information About the Role7-3:30 M-F1-2 holidays/year callevery 6-8 weekend callAdditional Preferred RequirementsOR experience PreferredOverview... more

    5 Days Ago

  • BJC Healthcare | Saint Louis, MO

    NURSE CLINICAL

    BJC Healthcare | Saint Louis, MO

    Job Description. Additional Information About the Role. \n. \n. \n. \n. Cardiothoracic/Cardiology. floor. Must have a background in this field . \n. \n. Ad... more

    26 Days Ago

  • BJC HealthCare | Ballwin, MO

    Clinical Nurse

    BJC HealthCare | Ballwin, MO

    Additional Information About the Role Additional Preferred Requirements Overview Christian Hospital has been serving St. Louis and the surrounding metro ar... more

    5 Days Ago

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Where Does Our Salary Data Come From?

Salary.com salary estimates, histograms, trends, and comparisons are derived from both employer job postings and third-party data sources. We also provide multiple percentiles of salary information for your reference, click here to know Why the Salary Midpoint Formula Is Crucial to Getting Pay Equity Right. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.

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